Multifaceted Applications of Chitosan in Cancer Drug Delivery and Therapy

نویسندگان

  • Anish Babu
  • Rajagopal Ramesh
چکیده

Chitosan is a versatile polysaccharide of biological origin. Due to the biocompatible and biodegradable nature of chitosan, it is intensively utilized in biomedical applications in scaffold engineering as an absorption enhancer, and for bioactive and controlled drug release. In cancer therapy, chitosan has multifaceted applications, such as assisting in gene delivery and chemotherapeutic delivery, and as an immunoadjuvant for vaccines. The present review highlights the recent applications of chitosan and chitosan derivatives in cancer therapy.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Green synthesis of Iron oxide nanoparticles using carum carvi L. and modified with chitosan in order to optimize the anti-cancer drug adsorption

Magnetic iron oxide nanoparticles have gained a lot of attention in drug delivery systems because they can control a drug pathway to deliver it to the specific site under a magnetic field which is related to their magnetic core and surface coating. Chitosan-coated FeNPs, have prominent antimicrobial and biological properties that make chitosan a promising biopolymer for drug delivery applicatio...

متن کامل

Green synthesis of Iron oxide nanoparticles using carum carvi L. and modified with chitosan in order to optimize the anti-cancer drug adsorption

Magnetic iron oxide nanoparticles have gained a lot of attention in drug delivery systems because they can control a drug pathway to deliver it to the specific site under a magnetic field which is related to their magnetic core and surface coating. Chitosan-coated FeNPs, have prominent antimicrobial and biological properties that make chitosan a promising biopolymer for drug delivery applicatio...

متن کامل

Doxorubicin Loaded DNA Aptamer Linked Myristilated Chitosan Nanogel for Targeted Drug Delivery to Prostate Cancer

Recently, specific attention has been paid to aptamers, short DNA or RNA, as a tool for cancer diagnosis and therapy. In the present study MCS nanogels were prepared by Myristate: chitosan at 1:9 ratio and were characterized by several techniques. A selected ssDNA aptamer(Apt) capable of detecting LNCaP cells was linked to Myristilated chitosan nanogels (Apt-MCS) by glutaraldehyde and loaded wi...

متن کامل

Doxorubicin Loaded DNA Aptamer Linked Myristilated Chitosan Nanogel for Targeted Drug Delivery to Prostate Cancer

Recently, specific attention has been paid to aptamers, short DNA or RNA, as a tool for cancer diagnosis and therapy. In the present study MCS nanogels were prepared by Myristate: chitosan at 1:9 ratio and were characterized by several techniques. A selected ssDNA aptamer(Apt) capable of detecting LNCaP cells was linked to Myristilated chitosan nanogels (Apt-MCS) by glutaraldehyde and loaded wi...

متن کامل

A Critical Comparison Study on the pH-Sensitive Nanocomposites Based on Graphene-Grafted Chitosan for Cancer Theragnosis

Abstract Drug delivery is one of the major issues in the world of science, which receives a large part of the research in various fields. The ultimate goal of drug delivery is to help the patient with developing advanced drug delivery systems. These systems revolutionize the treatment of many diseases including cancer. Effective drug carriers can significantly reduce the undesirable side effec...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2017